| 原发性肝癌患者庚型肝炎病毒感染的临床研究 |
| |
| 引用本文： | 魏群,张弘,黄介飞,江枫,倪润洲,肖明兵.原发性肝癌患者庚型肝炎病毒感染的临床研究[J].南通医学院学报,2001,21(2):134-134. |
| |
| 作者姓名： | 魏群 张弘 黄介飞 江枫 倪润洲 肖明兵 |
| |
| 作者单位： | 南通医学院附属医院消化内科 |
| |
| 摘 要： | 目的：探讨原发性肝癌患者庚型肝炎病毒（HGV）感染的分布。方法：根据中国株HGV5’端非编码序列设计引物，采用逆转录套式聚合酶链反应方法。用此技术对107例原发性肝癌、45例慢性肝炎、43例肝硬化患者血清进行了检测分析。结果：107例原发性肝癌患者中有10例HGV－RNA阳性（9．3％）；45例慢性肝炎患者中有5例HGV－RNA阳性（11．1％）；43例肝硬化患者中有3例HGV－RNA阳性（7．0％）。结论：庚型肝炎病毒感染可能与原发性肝癌发生有一定关系，但不是引起肝癌的主要的因素。
|
| 关 键 词： | 庚型肝炎病毒 原发性肝癌 逆转录套式聚合酶链反应 |
| 文章编号： | 1000-2057(2001)02-0134-01 |
| 修稿时间： | 2001年1月4日 |
CLINICAL RESEARCH ON HGV INFECTION IN CASES WITH PRIMARY HEPATOCELLULAR CARCINOMA |
| |
| WEI Qun,ZHANG Hong,HUANG Jiefei,et al.CLINICAL RESEARCH ON HGV INFECTION IN CASES WITH PRIMARY HEPATOCELLULAR CARCINOMA[J].ACTA Academiae Medicinae Nantong,2001,21(2):134-134. |
| |
| Authors: | WEI Qun ZHANG Hong HUANG Jiefei |
| |
| Abstract: | Objective:To investigate the prevlence of hepatitis G virus (HGV) infection in the cases with primary Hepat- ocellular carcinoma (PHC) .Methods: Two pairs of primers were designed based on the sequence of the 5'non-coded region of Chinese HGV isolated and HGV-RNA was detected with RT-PCR. Serum specimens 107 cases with PHC,45 cases with chronic hepatitis and 43 cases with liver cirrhosis were tested. Results: HGV was positive in 10(9.3%)out of 107 cases with PHC; 5(11.1%) out of 45 cases with chronic hepatitis; 3(7.0%) out of 43 cases with liver cirrhosis.Conclusion: There may be some relationship between HGVinfection and PHC,but HGV infectionis may be not the main cause of PHC. |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
