| 大环内酯类抗生素的发展与展望 |
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| 引用本文： | 郑忠辉,石和鹏,金洁,刘浚.大环内酯类抗生素的发展与展望[J].药学进展,2005,29(1):1-7. |
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| 作者姓名： | 郑忠辉 石和鹏 金洁 刘浚 |
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| 作者单位： | 中国医学科学院,中国协和医科大学,医药生物技术研究所,北京,100050 |
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| 摘 要： | 简要介绍大环内酯类抗生素发展近况,讨论了大环内酯类抗生素的作用机制、耐药机制、构效关系及泰利霉素(Telithromycin)和ABT-773(Cethromycin,喹红霉素)的药理、临床性质。
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| 关 键 词： | 大环内酯 酮内酯 泰利霉素 ABT-773 |
| 文章编号： | 1001-5094(2005)01-0001-07 |
The Development and the Prospect of Macrolide Antibiotics |
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| ZHENG Zhong-hui,SHI He-peng,JIN Jie,LIU Jun.The Development and the Prospect of Macrolide Antibiotics[J].Progress in Pharmaceutical Sciences,2005,29(1):1-7. |
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| Authors: | ZHENG Zhong-hui SHI He-peng JIN Jie LIU Jun |
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| Abstract: | The Development of Macrolide Antibiotics was introduced briefly and the action mechanism, structure-activity relationships, and resistant mechanisms of the macrolides were discussed. The pharmacological and clinical characteristics of Telithromycin and ABT-733 (Cethromycin) were reviewed as well. |
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| Keywords: | Macrolide Ketolide Telithromycin ABT-773 |
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