| 半枝莲的化学成分研究（Ⅰ） |
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| 引用本文： | 陈艳,张国刚,毛德双,李英娜. 半枝莲的化学成分研究（Ⅰ）[J]. 中国药物化学杂志, 2008, 18(1): 48-50 |
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| 作者姓名： | 陈艳 张国刚 毛德双 李英娜 |
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| 作者单位： | 1. 沈阳药科大学,中药学院,辽宁,沈阳,110016
2. 辽宁东宁药业有限公司,辽宁,阜新,123000 |
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| 摘 要： | 目的研究半枝莲（Scutellaria barbaraD．Don）的化学成分。方法从半枝莲全草的乙醇提取液中分离得到9个化合物。利用理化性质和波谱学分析，鉴定它们的化学结构。结果分离鉴定了9个化合物，分别是6-羟基香豆素（1）、香草酸（2）、异香草酸（3）、4＇-羟基汉黄芩素（4）、6-甲氧基柚皮素（5）、芹菜素（6）、柚皮素（7）、木犀草素（8）、异红花素（9）。结论化合物1为首次从该属植物中分得的已知化合物，化合物2、3为首次从该植物中分得的已知化合物。
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| 关 键 词： | 结构鉴定 柱色谱 波谱分析 半枝莲 乙醇提取物 |
| 文章编号： | 1005-0108（2008）01-0048-03 |
| 收稿时间： | 2007-04-30 |
| 修稿时间： | 2007-04-30 |
Chemical constituents of Scutellaria barbata D.Don(Ⅰ) |
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| CHEN Yan,ZHANG Guo-gang,MAO Des-huang,LI Ying-na. Chemical constituents of Scutellaria barbata D.Don(Ⅰ)[J]. Chinese Journal of Medicinal Chemistry, 2008, 18(1): 48-50 |
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| Authors: | CHEN Yan ZHANG Guo-gang MAO Des-huang LI Ying-na |
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| Affiliation: | School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang 110016, China |
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| Abstract: | Aim To investigate the chemical constituents of Scutellaria barbata D. Don. Methods Nine compounds were separated from the whole plant and their structures were identified by the spectral analysis and chemical evidence. Results Nine compounds were isolated and identified as 6-hydroxycoumarin (1), vanillic acid (2), isovanillic acid,(3) 4’-hydroxywogonin (4), 6-methoxynaringenin (5), apigenin (6), naringenin (7), luteolin (8), isocarthamidin (9). Conclusions Compound 1 was isolated from Scutellaria for the first time, while compound 2 and 3 were isolated from Scutellaria barbata D. Don for the first time. |
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| Keywords: | structural identification column chromatography spectroscopy analysis Scutellaria barbata D.Don ethanolic extract |
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