痉挛性斜颈患者瞬目反射的电生理研究

目的探讨痉挛性斜颈瞬目反射的电生理变化。方法 30例痉挛性斜颈患者及30例正常对照（颈部向左侧扭转）瞬目反射双侧R1、R2潜伏期、波幅高比较分析。结果病例组瞬目反射R1、R2潜伏期、R1波幅高正常,双侧R1、R2潜伏期、R1波幅高无统计学差异,斜颈同侧R2波幅高于对侧,有统计学差异;正常对照组颈部向左侧扭转时R1、R2潜伏期,R1、R2波幅高双侧比较无统计学差异。结论瞬目反射R1、R2潜伏期正常,提示该反射弧结构完整,斜颈同侧R2波幅高于对侧表明该侧上段延髓的外侧、桥脑中间神经元过度兴奋,痉挛性斜颈患者存在脑干功能失调。

Study on blink reflex in Patients with spasmodic torticollis

Objective To futher elucidate the pathogenesis of spasmodic torticollis.Methods Blink reflex was investigated in 30 patients affected ST and 30 normal subjects.Latency and amplitude of R1、R2 was compared between Ipsilateral to torticollis and contralateral to torticollis in 30 patients with ST,Latency and amplitude of R1、R2 was compared between the left and right sides in 30 normal subjects.Results All ST patients presented normal R1、R2 latency and R1 amplitude,No significant difference was found between ipsilateral to torticollis and contralateral to torticollis.Ipsilateral R2 amplitude was greater in patients than R2 amplitude contralateral to torticollis.R1、R2 latency and R1、R2 amplitude did not differ significantly between the left and right sides in 30 normal subjects.Conclusion By the means of BR,normal R1、R2 latency indicate that the structure of reflex arc is complete,That ipsilateral R2 amplitude was greater in patients than R2 amplitude contralateralto torticollis indicate that increases exci-tability of brainstem interneuronal pathways mediated the R2 com-ponent.