Peripheral T-cell lymphoma involving subcutaneous tissue |
| |
Authors: | K-H CHO J-K OH C-W KIM D-S HEO† S-T KIM‡ |
| |
Institution: | Department of Dermatology Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu. Seoul 110-744 Korea;Department of Pathology Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu. Seoul 110-744 Korea;Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu. Seoul 110-744 Korea;Department of Dermatology, Kosin Medical College, Pusan. Korea |
| |
Abstract: | The peripheral T-cell lymphomas, presumably derived from various immunocompetent peripheral T-cell system components, form a heterogeneous group of non-Hodgkin's lymphomas. We describe two patients with peripheral T-cell lymphoma primarily involving subcutaneous tissue. They presented with multiple subcutaneous nodules. Skin biopsy specimens in both patients demonstrated a lobular subcutaneous infiltrate. The infiltrate consisted of small and medium-sized atypical lymphoid cells. Both patients had a protracted clinical course before they were diagnosed as having malignant lymphoma. We detected latent Epstein-Barr virus infection in the skin lesions of case 2. Latent Epstein-Barr virus infection might be related to the development of this variant of peripheral T-cell lymphoma. |
| |
Keywords: | |
|
|