Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor |
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Authors: | Messina Mario Severi Filiberto M Buonocore Guiseppe Molinaro Francesco Amato Giovanna Petraglia Felice |
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Institution: | a Section of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Policlinico “Le Scotte”, 53100 Siena, Italy b Section of Neonatology, Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Policlinico “Le Scotte”, 53100 Siena, Italy c Section of Obstetrics and Reproductive Medicine, Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Policlinico “Le Scotte”, 53100 Siena, Italy |
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Abstract: | ObjectiveCongenital gingival granular cell tumor (CGCT) is a rare benign lesion appearing at birth on the alveolar median ridge of the maxilla. Etiology is still unclear because spontaneous regression of the lesion is rare.MethodsThe present report describes 2 cases of neonatal CGCT, highlighting benefits of ultrasonography to treatment of the prenatally diagnosed lesion.ResultsThe patients immediately underwent surgical exeresis. Pathology revealed a tumor of large polyedric cells with vacuolar central nuclei and eosinophil granular cytoplasm.ConclusionsPrenatal diagnosis is fundamental in the therapeutic approach to CGCT: ultrasonography methodologies allow diagnosis of the lesion in the uterus at the 36th gestational week, thus also allowing planning of delivery and, immediately later, the surgical treatment. That permits planning of delivery in a third-level center with considerable benefit for both the mother and the newborn. |
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Keywords: | Congenital epulis Granular cell rabdioma Myoblastoma Oral tumor |
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