Treatment of toxic epidermal necrolysis in a pediatric patient with a nanocrystalline silver dressing |
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Authors: | Asz José Asz Daniel Moushey Robin Seigel Jennifer Mallory Susan B Foglia Robert P |
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Affiliation: | a Division of Pediatric Surgery and Pediatric Acute Wound Service, St Louis Children's Hospital and Washington University School of Medicine, St Louis, MO, USA b Division of Dermatology, St Louis Children's Hospital and Washington University School of Medicine, St Louis, MO, USA c Department of Dermatology, Hospital General “Dr. Manuel Gea Gonzalez”, Mexico City, Mexico d Department of Pediatric Surgery, Children's Medical Center Dallas, Dallas, TX, USA |
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Abstract: | Background/PurposeTo report a case of toxic epidermal necrolysis (TEN) involving 90% body surface area, successfully treated with a nanocrystalline silver dressing (Acticoat, Smith & Nephew, Largo, FL).MethodsA review of the hospital and acute wound center patient records and the recent English medical literature regarding TEN and nanocrystalline silver dressing.ResultsWe found only 1 report of TEN treated with a nanocrystalline silver dressing. The nanocrystalline silver dressing was both effective in preventing wound infection and convenient for treating our patient with TEN.ConclusionThe use of nanocrystalline silver dressing should be considered for the treatment of TEN. |
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Keywords: | Toxic epidermal necrolysis (TEN) Stevens-Johnson syndrome (SJS) Nanocrystalline silver dressing Acticoat Pediatric |
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