| 56例甲状腺功能亢进症患者的骨代谢生化指标分析 |
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| 引用本文： | 温宇明. 56例甲状腺功能亢进症患者的骨代谢生化指标分析[J]. 内科, 2012, 7(4): 341-343 |
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| 作者姓名： | 温宇明 |
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| 作者单位： | 广东省佛山市南海区大沥医院内科,佛山市,528231 |
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| 摘 要： | 目的探讨甲状腺功能对骨代谢的影响。方法对56例甲状腺功能亢进（简称甲亢）患者及56例健康对照者采用化学发光法和放射免疫法（RIA）测定血FT3、FT4、PINP、BGP、ICTP、B-ALP。结果甲亢患者血bFT3、FT4、PINP、BGP、ICTP、B-ALP活性较健康对照组明显增高（P〈0．01），且甲亢患者血FT3、FT4分别与PINP、BGP、ICTP、B-ALP呈正相关（P〈0．01）。结论甲状腺激素可能直接参与加速骨转换及增加骨吸收，由此导致甲亢患者骨量丢失。
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| 关 键 词： | 甲状腺功能亢进症 骨质疏松症 骨代谢。 |
Analysis of bone metabolism-associated biochemical markers in 56 hyperthyroid patients |
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| WEN Yu-ming. Analysis of bone metabolism-associated biochemical markers in 56 hyperthyroid patients[J]. Internal Medicine of China, 2012, 7(4): 341-343 |
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| Authors: | WEN Yu-ming |
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| Affiliation: | WEN Yu-ming(Department of Internal Medicine,Dali People′s Hospital of Nanhai District,Foshan City,Guangdong Province,Foshan 528231,China) |
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| Abstract: | Objective To explore the effect of thyroid function on bone metabolism.Methods Serum concentrations of FT3,FT4,PINP,BGP,ICTP,B-ALP are measured by radioimmunoassay(RIA)in 56 hyperthyroid patients and 56 healthy controls.Results The levels of FT3,FT4,PINP,BGP,ICTP,B-ALP in hyperthyroid patients significantly higher than those of the healthy controls(P<0.01),and the levels of FT3,FT4 were positively correlated to PINP,BGP,ICTP,B-ALP respectively(P<0.01).Conclusion Thyroid hormone might speed up bone turn over directly with increased bone resorption to induce bone mass loss in patients with hyperthyroid. |
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| Keywords: | Hyperthyroidism Osteoporosis Bone metabolism |
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