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PET/CT在肺癌诊断中价值初探
引用本文:蔡莉,张驰,张志强,李菲,张海英,周卫华.PET/CT在肺癌诊断中价值初探[J].中国医学装备,2013(1):90-91.
作者姓名:蔡莉  张驰  张志强  李菲  张海英  周卫华
作者单位:武警总医院核医学科;武警总医院医学工程科
摘    要:目的:探讨PET/CT在肺癌诊断中的应用价值。方法:回顾性分析98例肺部结节患者的PET/CT检查,结合患者的临床及病理检查判断PET/CT对肺癌诊断符合率。结果:PET/CT诊断结果,恶性病变79例,其中48例有病理诊断,鳞癌18例,腺癌15例,小细胞肺癌14例,类癌1例。肺门、纵隔淋巴结转移34例,肺内转移10例,胸膜转移12例,多发骨转移18例,脑部转移1例,确诊为良性病变19例。PET/CT对肺癌诊断的灵敏度、特异度以及诊断准确率分别为98.7%、94.7%、98.0%。结论:PET/CT能够较准确的诊断肺部疾病,在肺部病灶的良、恶性鉴别和疾病分期有突出的临床实用价值。

关 键 词:正电子发射断层显像术  体层摄影术  X线计算机  肺癌  诊断

Application of (18)~FDG PET/CT in diagnosis of lung cancer
Institution:CAI Li, ZHANG Chi, ZHANG Zhi-qiang, et al Department of Nuclear Medicine, General Hospital of Chinese Armed Police Forces, Beijing 100039, China.
Abstract:Objective: To evaluate the clinical value of (18)~FDG PET/CT in patients with lung cancer. Methods: Serial PET imagings were performed in 98 patients with pulmonary nodule. Diagnosis accuracy was got based on pathological and clinical findings. Results: Among 98 cases 79 were diagnosed as malignant by PET/CT, of those 48 were confirmed with pathological findings: (18)~lung squamous cell carcinoma, 15 lung adenocarcinoma, 14 small cell lung cancer, and 1 carcinoid tumor. Metastases were detected in different sites: there were 34 cases with hilar and mediastinal nodal metastasis, 10 with pulmonary metastasis, 12 with pleural metastasis, (18)~with bone metastasis, and 1 with brain metastases. 19 cases were diagnosed as benign. The sensitivity, specificity and diagnosis accuracy of FDG PET/CT in the diagnosis of lung cancer were 98.7%, 94.7%, 98.0%, respectively. Conclusion: From the study it can be concluded that PET/CT could diagnose pulmonary disease with better accuracy and might be useful in differential diagnosis and staging of lung cancer.
Keywords:Positron-emission tomography  Tomography  X-ray computed  Lung cancer  Diagnosis
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