| Abstract: | Modelled venous insufficiency of the hind limbs of cats (ligation of the posterior vena cava for 4-6 weeks) led to structural reorganization of the venous walls of the gastrocnemius muscle, which was manifested by a sharp increase of stretchability of the venous bed of the muscle if the activity of the smooth muscles was removed by papaverine, and by significant loss of the sensitivity of the smooth muscles of the intramuscular veins to noradrenaline as regards function. The range of adrenergic changes of postcapillary resistance and capillary pressure was reduced sharply in animals with venous insufficiency. This may be among the causes of disorders of metabolic processes in the skeletal muscles in venous insufficiency. |
