北京地区肺癌患者血硒水平研究 II.肺癌患者血硒水平及影响因素分析

对北京地区１００例肺癌患者及１００例健康对照血清硒水平影响因素的研究表明：肺癌患得血清硒水平显著低于健康人群；肺癌患者血清硒水平与病变范围呈负相关、与吸烟指数呈负相关、与患者的营养状态呈正相关，病情加重时血清硒含量下降，病情缓解时血清硒含量回升。提示肺癌患者的低硒状态主要由肺癌本身引起，吸烟可以加重肺癌患者的低硒状态。

Studies on the Correlation of Blood Selenium and Lung Cancer II. An Analysis of Serum Selenium Levels and Influencing Factors in Patients with Lung Cancer

This paper reports the serum selenium concentration in 100 cases of lung cancer patients and 100 healthy controls. The results showed that the serum selenium level in patients with lung cancer was signifcantly lower than that of controls. Serum selenium level in lung cancer patients was inversely related to the stage of cancer, the amount of tabacco abuse and the serum Cu level. It was positively correlated with patient''s nutritional status and the serum albumin level. Serum selenium level was decreased with cancer progression and increased with disease remission. These results suggest that the lower serum selenium level in lung cancer patients was the result rather than the cause of cancer.