Value of high resolution real-time ultrasonography in secondary hyperparathyroidism |
| |
| Authors: | O H Clark D A Stark Q Y Duh C D Arnaud G A Gooding |
| |
| Affiliation: | 1. San Francisco, California, USA;2. Boston, Massachusetts, USA;1. UMR 7266 Littoral, Environnement et Sociétés (CNRS - Université de La Rochelle), Institut du littoral et de l''environnement, 2 rue Olympe de Gouges, 17000 La Rochelle, France;2. UMR 5281 Acteurs, Ressources et Territoires dans le Développement (CNRS – Université de Montpellier 3 – CIRAD – Université de Montpellier – Université de Perpignan Via Domitia), Route de Mende, 34199 Montpellier Cedex 5, France;3. Université de Nantes, Laboratoire Mer, Molécules et Santé EA 2160, Faculté des Sciences, 2 rue de la Houssinière, 44322 Nantes Cedex 3, France;4. EA 4270 Centre de Recherche Interdisciplinaire en Histoire, Histoire de l’Art et Musicologie (Université de Poitiers – Université de Limoges), 8 rue René Descartes, 86022 Poitiers Cedex, France;5. Harte Research Institute for Gulf of Mexico Studies, Texas A&M University-Corpus Christi, 6300 Ocean Drive, Unit 5869, 78412 Corpus Christi, TX, USA;6. UMI 3376 Takuvik, CNRS/Université Laval, Département de Biologie, Pavillon Alexandre-Vachon, 1045 Avenue de la Médecine, local 2078, Université Laval, Québec (Québec), G1V 0A6, Canada;1. Istituto di Geoscienze e Georisorse, IGG-CNR, Via Moruzzi 1, 56126, Pisa, Italy;2. Istituto Nazionale di Geofisica e Vulcanologia INGV, Via della Faggiola 32, 56126, Pisa Italy;3. Dipartimento di Scienze della Terra, University of Pisa, Via S. Maria 53, 56126, Pisa, Italy;4. CIRSEC Centre for Climatic Change Impact, University of Pisa, Pisa, Italy;5. Istituto di Geologia Ambientale e Geoingegneria, IGAG-CNR, Via Salaria km29.4, Monterotondo, Rome, Italy;6. Dipartimento di Scienze della Terra, Università di Torino, Via Valperga Caluso 35, 10125, Torino, Italy;7. School of Geography, University of Melbourne, Victoria, 3010, Australia;8. School of Earth Sciences, University of Melbourne, Victoria, 3010 Australia;9. Associazione Gruppi Speleologici Piemontesi AGSP-Club Alpino Italiano, Torino, Italy;1. Heritage Research Center, Stephen F. Austin State University, USA;2. Cultural Heritage Department, Jean Monnet University, France;3. Cox|McClain Environmental Consulting, Inc., USA;4. Department of Anthropology, Texas State University, USA;5. GAES, University of the Witwatersrand, South Africa;6. Archeological & Environmental Consultants, LLC, USA |
| |
| Abstract: | Thirty-two patients were treated surgically for symptomatic secondary or tertiary hyperparathyroidism, and 27 of these patients had high resolution (10 mHz) real-time ultrasonography before parathyroidectomy. This preoperative localization study identified one or more enlarged hyperplastic parathyroid glands in all but one patient who had not had a previous parathyroid operation, and in five of six patients who did have previous parathyroid operations. In both of the patients in whom no parathyroid glands were identified by ultrasonography the only abnormal enlarged parathyroid glands were those situated within the superior mediastinum. When large glands are not observed by ultrasonography in patients with severe secondary hyperparathyroidism, the glands are usually situated in the superior mediastinum, behind the trachea or esophagus, or deeply within the neck. The size of the parathyroid glands correlated positively with the serum parathyroid hormone level and with the severity of the secondary hyperparathyroidism. Thus, the preoperative identification of parathyroid glands by ultrasonography not only localizes the site of most hyperplastic parathyroid glands (70 percent of patients), but also detects those patients who have enlarged parathyroid glands, elevated serum parathyroid hormone levels, and severe secondary hyperparathyroidism. These are the patients who are thus unlikely to respond to further medical therapy. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
