| 替比夫定与HBIG联用预防肝移植术后乙型病毒性肝炎复发的疗效 |
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| 引用本文： | 汪根树,李华,张琪,张剑,姜楠,汪国营,傅斌生,王冰,金海,杨扬,陈规划.替比夫定与HBIG联用预防肝移植术后乙型病毒性肝炎复发的疗效[J].器官移植,2011,2(6):314-316,353. |
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| 作者姓名： | 汪根树 李华 张琪 张剑 姜楠 汪国营 傅斌生 王冰 金海 杨扬 陈规划 |
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| 作者单位： | 中山大学附属第三医院肝移植中心中山大学器官移植研究所广东省器官移植中心,广州,510630 |
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| 基金项目： | 国家重点基础研究发展规划项目(973分课题)(2009CB522404); 十一五科技攻关项目(2008ZX10002-026); 广东省科技计划项目(2008A060202007) |
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| 摘 要： | 目的 评价替比夫定与乙型肝炎人免疫球蛋白(HBIG)预防肝移植术后乙型病毒性肝炎(乙肝)复发的疗效和安全性.方法 26例乙肝相关终末期肝病患者,其中HBV 脱氧核糖核酸(DNA)阳性者12例,乙型肝炎表面抗原(HBsAg)阳性20例,乙型肝炎e抗原(HBeAg)阳性7例.无YMDD变异阳性病例.患者均联合应用替比夫定和...
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| 关 键 词： | 替比夫定 肝移植 乙型病毒性肝炎 复发 乙型肝炎病毒 周围神经病 肌病 |
Effect of joint use with telbivudine and hepatitis B immune globulin on prophylaxis of hepatitis B recurrence after liver transpalatation |
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| WANG Gen-shu,LI Hua,ZHANG Qi,ZHANG Jian,JIANG Nan,WANG Guo-ying,FU Bin-sheng,WANG Bing,JIN Hai,YANG Yang,CHEN Gui-hua.Effect of joint use with telbivudine and hepatitis B immune globulin on prophylaxis of hepatitis B recurrence after liver transpalatation[J].Ogran Transplantation,2011,2(6):314-316,353. |
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| Authors: | WANG Gen-shu LI Hua ZHANG Qi ZHANG Jian JIANG Nan WANG Guo-ying FU Bin-sheng WANG Bing JIN Hai YANG Yang CHEN Gui-hua |
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| Institution: | WANG Gen-shu,LI Hua,ZHANG Qi,ZHANG Jian,JIANG Nan,WANG Guo-ying,FU Bin-sheng,WANG Bing,JIN Hai,YANG Yang,CHEN Gui-hua. Liver Transplantation Center,Third Affiliated Hospital of Sun Yat-sen University,Organ Transplantation Institute of Sun Yat-sen University,Organ Transplantation Research Center of Guangdong Province,Guangzhou 510630,China |
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| Abstract: | Objective To investigate the effect and safety of joint use of telbivudine(TBV) and hepatitis B immune globulin(HBIG) on prophylaxis of hepatitis B recurrence after liver transplantation. Methods Twenty-six patients with hepatitis B related end-stage liver disease were chosen, including 12 cases with hepatitis B virus(HBV)-deoxyribonucleic acid(DNA) positive, 20 with hepatitis B surface antigen(HBsAg) positive, 7 with hepatitis B e antigen(HBeAg) positive and no case with YMDD variation positive. TBV and HB... |
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| Keywords: | Telbivudine Liver transplantation Hepatitis B Recurrence Hepatitis B virus Peripheral neuropathy Myopathy |
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