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Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
Authors:Peter Horak  Andrew R. Crawford  Douangsone D. Vadysirisack  Zachary M. Nash  M. Phillip DeYoung  Dennis Sgroi  Leif W. Ellisen
Affiliation:aMassachusetts General Hospital Cancer Center, and Harvard Medical School, Boston, MA 02114; and ;bDepartment of Pathology, Massachusetts General Hospital, Boston, MA 02114
Abstract:
Keywords:hypoxia   mTOR   mitochondria   breast cancer   tuberous sclerosis
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