2009-2012年中国艾滋病哨点监测人群丙型肝炎病毒感染状况分析

目的分析中国艾滋病哨点监测8类人群丙型肝炎病毒(HCV)感染状况.方法在2009-2012年哨点监测期内(每年4-6月)以重复横断面调查的方法,对吸毒者、男男性行为者、暗娼、性病门诊男性就诊者、男性长途汽车司乘人员、男性流动人口、孕产妇和青年学生8类人群开展艾滋病哨点监测,同时采集血样进行HIV、梅毒、HCV抗体检测.结果2009-2012年监测哨点中吸毒人群HCV抗体总阳性率较高(40.0%～ 43.0%),其中注射吸毒者HCV抗体总阳性率为55.0%～ 65.0%,并呈上升趋势；其他7类哨点人群HCV抗体总阳性率维持在较低水平(近三年均<1.0%).结论HCV主要在吸毒人群中流行,其他7类哨点人群的HCV抗体总阳性率均维持在较低水平.HCV的传播途径主要为经血传播,注射吸毒是HCV经血传播的主要方式之一.

HCV prevalence among the populations under the HIV sentinel surveillance data from 2009 to 2012 in China

Objective To analyze the hepatitis C virus (HCV) prevalence among 8 populations in 2009-2012 in China,using the HIV sentinels surveillance data.Methods Cross-sectional studies had been repeatedly conducted on HIV Sentinel Surveillance with uniformed questionnaire and collection of venous blood specimen among 8 populations including drug users (DUs),men who have sex with men (MSM),female sex workers (FSW),male STD clinic attendees,male long distance truck drivers,male mobile populations,pregnant women and young students from April to June 2009 to 2012 on the yearly base.Blood testing for HIV,syphilis and HCV infections have been routinely performed on all participants of 8 populations recruited during the surveillance period.Results HCV prevalence among drug users had been relatively high,between 40.0%-43.0% in 2009-2012.HCV prevalence of injection drug users (IDUs) showing a slight increasing trend in the past four years from 55.0% in 2009 to 65.0% in 2012.HCV prevalence rates among other 7 populations maintained low remained less than 1.0% in the past three years.Conclusion Data from sentinel surveillance programs showed that HCV prevalence of DUs maintained high but the other 7 populations at low levels in the HIV sentinel surveillance areas in China.Blood-borne was the most common transmission pathways of HCV.IDU was one of the predominant models of HCV transmission in China and continued to fuel the HCV epidemics throughout the country.