不孕症妇女子宫内膜异位症危险因素对照研究分析

目的：探讨不孕妇女子宫内膜异位症患病高危因素及变化情况。方法以病例对照研究方法，选取2007—2012年在该院就诊的不孕症妇女810例，经腹腔镜确诊的250例子宫内膜异位症患者及同期不孕症正常盆腔153例为对照研究，进行子宫内膜异位症患病危险因素的条件Logisitic回归分析。结果调查的不孕妇女中子宫内膜异位症的患病率30.86%；不孕病程、体重指数、经期长短、月经周期长短、月经形式、子宫内膜异位症家族史、痛经程度、经量、性交痛、口服避孕药、妊娠史、盆腔痛等因素，研究组与对照组间差异有统计学意义（P〈0.05）。多因素Logisitic回归分析显示：年龄、不孕病程、体重指数、痛经、盆腔痛、性交痛、子宫内膜异位症家族史与子宫内膜异位症的风险因素有关。结论在不孕症妇女子宫内膜异位症发病因素中体重指数较低、子宫内膜异位症家族史、月经史、盆腔痛等相关因素起重要作用。妊娠次数多提示是子宫内膜异位症的保护因素。

Controlled Study and Analysis of the Risk Factors of Infertile Women with Endometriosis

Objective The aim of this study is to explore the risk factors related to endometriosis among infertile women and the varia-tion. Methods A case-control study was designed based on the data of 810 cases of infertile women admitted in Women＆amp;Infants Hos-pital of Zhengzhou from 2007 to 2012.According to the laparoscopy findings, 250 cases of women diagnosed with endometriosis and 153 cases of infertile women with normal pelvis were selected as the subjects for the controlled study.Logistic regression analysis was used to analyze the risk factors related to endometriosis. Results The prevalence of endometriosis in infertile women was 30.86%. There were statistically significant differences between the study group and the control group in infertility duration, body mass index, menstru-al length, the length of the menstrual cycle, menstrual form, the family history of endometriosis, dysmenorrhea extent, menstrual volume, dyspareunia, oral contraceptives, pregnancy history, pelvic pain, and other factors （P〈0.05）. Multi-factor logistic regression analysis showed that age, duration of infertility, body mass index, dysmenorrhea, pelvic pain, dyspareunia, and the family history of endometrio-sis are the risk factors related to endometriosis. Conclusion Low BMI value,a family history of endometriosis, menstrual history and pelvic pain are high risk factors of the infertile women with endometriosis, whereas multi-pregnancy is a protective factor of en-dometriosis.