前列地尔治疗糖尿病周围神经病变的疗效观察

目的：研究分析前列地尔（曼新妥）对糖尿病周围神经病变的治疗效果。方法随机将糖尿病周围神经病变的患者102例分为2组，对照组采用甲钴胺治疗，实验组在对照组基础上使用前列地尔治疗，对比观察两组疗效。结果实验组51例，总有效率为94.23%，高于对照组患者，差异有统计学意义（P＜0.05）；患者正中神经运动传导速度和感觉传导速度均高于对照组，差异有统计学意义（P＜0.05）。结论使用前列地尔对糖尿病周围神经病变具有较好的疗效，可以提高治疗效果，加快神经传导速度，值得应用。

Observation on the Efficacy of Alprostadil in the Treatment of Diabetic Pe-ripheral Neuropathy

Objective To study and analyze the effect of alprostadil on diabetic peripheral neuropathy. Methods 102 patients with diabetic peripheral neuropathy were randomly divided into two groups, the control group was treated with mecobalamine, the ex-perimental group was treated with alprostadil on the basis of the treatment of the control group. The efficacy of two groups was ob-served and compared. Results The total effective rate of 51 cases in the experimental group was 94.23%, higher than that of the patients in the control group（P〈0.05）;median nerve motor conduction velocity and sensory conduction velocity were higher than those of the control group （P〈0.05）, the differences were statistically significant. Conclusion Alprostadil has good effect on diabetic pe-ripheral neuropathy, which can improve the therapeutic effect, accelerate nerve conduction velocity, and is worthy of application.