针灸、推拿结合颈椎牵引对神经根型颈椎病患者痛感缓解及hs-CRP、IL-8、P物质的影响

目的:观察针灸、推拿结合颈椎牵引对神经根型颈椎病患者痛感缓解及超敏C反应蛋白(hs-CRP)、白细胞介素-8(IL-8)、血浆P物质的影响.方法:选择我院收治的112例神经根型颈椎病患者随机分为对照组和观察组各56例.对照组患者给予颈椎牵引;观察组患者则加用针灸、推拿结合颈椎牵引治之.观察两组的临床疗效,比较治疗前后患者临床症状变化,评估颈肩疼痛程度、强度、分级指数,监测用药前后hs-CRP、IL-8、P物质水平.结果:观察组的有效率高达91.1%,显著高于对照组的71.4%;观察组患者治疗后的中医证候积分显著低于对照组;观察组经治疗后VAS、PRI、PPI评分与对照组比较显著降低;观察组患者经治疗后hs-CRP、IL-8、P物质水平均显著低于对照组.结论:针灸、推拿结合颈椎牵引利于缓解神经根型颈椎病患者的颈椎痛感,减轻颈椎功能障碍,其机制与调控血清hs-CRP、IL-8、P物质水平以抑制炎性反应有一定相关性.

Research on the Influence of hs-CRP,IL-8, Substance P and Pain Relief for Treating Nerve-root Type Cervical Spondylosis Patients with Acupuncture and Moxibustion,Massage Combined with Cervical Traction

Objective To investigate the clinical efficacy of treating nerve-root type cervical spondylosis patients with acupuncture and moxibustion, massage combined with cervical traction, and explore the influence of hs-CRP, IL-8, substance P and pain relief . Methods 112 cases were randomly divided into a control group of 56 cases and an observation group of 56 cases. Patients in the control group were treated with cervical traction; while patients in the observation group were treated with acupuncture and moxibustion, massage combined with cervical traction. The paper was aimed at comparing the effectiveness, comparing the clinical symptom change, evaluating the neck and shoulder pain degree, classification index and intensity change, and testing the change levels of hs-CRP, IL-8 and substance P.Results The efficiency of the observation group was 91.1%, which was higher than that of the control group 71.4%; The observation group of TCM syndrome scores were significantly lower than the control group; the VAS, PRI and PPI scores and the levels of hs-CRP, IL-8 and substance P of the observation group were lower than that of the control group.Conclusion The therapy can effectively alleviate the neck and shoulder pain and re-duce cervical dysfunction. The mechanism may be associated with regulating hs-CRP, IL-8 and substance P levels to inhibit the inflammatory reaction.