Grave病相关肾病5例临床分析

目的探讨自身免疫性甲状腺疾病（AITD）相关肾病发病机制及临床病理特点。方法通过5例患者的诊治结合文献对该病进行综合分析。结果AITD肾病以蛋白尿为主，少数表现为肾病综合征和。肾炎综合征，病理表现多样化以膜性肾病、系膜增生性肾小球肾炎、局灶性肾小球硬化为主。结论治疗甲状腺疾病的同时加用免疫抑制剂效果良好。

Clinical analysis to 5 cases of graves disense related to nephrosis

Objective To investigate principle and clinic pathologic characteristics of autoimmune thyroid disease(AITD) associated nephrosis. Methods By introducing 5 cases and related reference to review clinic pathologic characteristics of AITD associated nephrosis. Results AITD associated nephrosis regard proteinuria as principal, and a handful of performance is nephritic syndrome and nephritis syndrome. Pathologic characteristics are diversity. It is usually membranous nephrology, mesangial proliferative glomerulonephritis and focal and sclerosing glomerulonephritis. Conclusion Treatment of AITD associated nephrosis itself and immunosuppressive agent therapy might be useful to get remission of it.