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益多酯治疗高脂血症283例的疗效
引用本文:胡丽霞,吴福娣,张新民.益多酯治疗高脂血症283例的疗效[J].中国新药与临床杂志,1987(3).
作者姓名:胡丽霞  吴福娣  张新民
作者单位:上海市胸科医院,上海市胸科医院,上海市胸科医院 上海 200030,上海 200030,上海 200030
摘    要:本文观察由上海第十六制药厂与延安制药厂供应的益多酯胶囊对283例高脂血症(CH>5.75mmol/l及或TG>1.98mmol/l)患者的疗效,经口服500mg/d,1-3mo后血CH及TG值分别平均下降0.87及1.5mmol/l(p<0.001),此外还能提高降低的血HDL-C值(≤0.5g/l),平均增高0.12g/l(p<0.001),有效率分别为50%,70%与66%,用药期间毒副反应比氯贝丁酯为轻。

关 键 词:益多酯  氯贝丁酯  胆固醇  甘油三酯类  高密度脂蛋白类

The therapeutic efficacy of etofylline clofibrate in 283 patients with hyperlipidemia
HU Li-Xia,WU Fu-Di,ZHANG Xin-Min.The therapeutic efficacy of etofylline clofibrate in 283 patients with hyperlipidemia[J].Chinese Journal of New Drugs and Clinical Remedies,1987(3).
Authors:HU Li-Xia  WU Fu-Di  ZHANG Xin-Min
Abstract:The therapeutic efficacy of etofylline clofibrate, provided by shanghai No. 16 and Yan-An Pharmaceutical factory has been studied in 283 patients with hyperlipidemia. Following oral administration 500mg/d 1-3 mo, the average value of high plasma CHand TG decreased 0.87 and 1.5mmol/l respectively (p< 0.001).Besides,it could increase the value of low plasma HDL-C(≤0.5g/L)as well, with an average 0.i2g/L(p<0.001).The rate of efficacy was 50%, 70% and 60% respectively. The course of medication, the side and toxical effects were far less than clofibrate.
Keywords:etofylline clofibrate  clofibrate  cholesterol  triglyceride  high density lipoproteins  
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