A test of state dependency effects in marihuana intoxication for the learning of psychomotor tasks

Cannabis cigarettes calibrated to deliver 7 mg ⁹-THC were administered to experienced cannabis users and to novices in a 2×2 state-dependency learning design using psychomotor tasks. Subjects given four training sessions under marihuana performed no better on the fifth (test) session with the drug than those subjects who had trained in the non-drug condition and were tested in the drug condition. Cannabis-induced impairment in the performance of these tasks is such that prior training in the non-drug condition appears to confer no advantage to the subject. There was no evidence of state-dependency effects in psychomotor performance between drug and non-drug conditions.