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大鼠腺垂体促肾上腺皮质激素细胞分泌方式的免疫电镜研究
引用本文:虞培玲,李肇特.大鼠腺垂体促肾上腺皮质激素细胞分泌方式的免疫电镜研究[J].解剖学杂志,1997(6).
作者姓名:虞培玲  李肇特
作者单位:北京友谊医院实验中心 北京100050
摘    要:实验用雄性Wistar大鼠,以在无菌条件下腹腔注射松节油的方法制成急性非特异性腹膜炎,取大鼠腺垂体用免疫电镜方法进行染色.发现促肾上腺皮质激素(ACTH)细胞内分泌颗粒向细胞表面突起,并可见细胞间隙内完整的金标记的内分泌颗粒,实验结果表明,ACTH细胞除传统认为的胞吐分泌外还有其它分泌方式.

关 键 词:促肾上腺皮质激素  腺垂体  分泌

IMMUNOELECTRONMICROSCOPIC STUDY OF SECRETORY WAYS OF ADRENOCORTICOTROPHIC HORMONE CELLS OF PITUITARY IN RATS
Yu Peiling,Li Zhaote Medical Experimental Center,Beijing Friendship Hospital,Beijing.IMMUNOELECTRONMICROSCOPIC STUDY OF SECRETORY WAYS OF ADRENOCORTICOTROPHIC HORMONE CELLS OF PITUITARY IN RATS[J].Chinese Journal of Anatomy,1997(6).
Authors:Yu Peiling  Li Zhaote Medical Experimental Center  Beijing Friendship Hospital  Beijing
Institution:Yu Peiling,Li Zhaote Medical Experimental Center,Beijing Friendship Hospital,Beijing 100050
Abstract:Male wistar rats were used to investigate the secretion of adrenocorticotrophic hormone (ACTH) cells of the pituitary in rats. Acute nonspecific peritonitis was induced by injecting tur-pentine to the peritoneal cavity under aseptic condition. The pituitary was stained with immuno-electronmicroscopic method. We found that some secretroy granules of ACTH cell, protruded to the cell surface, and that gold-labelled secretory granules occasionly appeared in the intercellular space. The finding indicate that there are other secretory ways besides exocytosis.
Keywords:adrenocorticotrophic hormone cell  pituitary
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