| 乙二醛对染毒大鼠抗氧化酶活力的影响 |
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| 引用本文： | 范来富,李富君,李革新,陈爱莉,刘轩军. 乙二醛对染毒大鼠抗氧化酶活力的影响[J]. 工业卫生与职业病, 2000, 26(4): 207-208 |
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| 作者姓名： | 范来富 李富君 李革新 陈爱莉 刘轩军 |
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| 作者单位： | 中国医科大学公共卫生学院,沈阳市,110001 |
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| 摘 要： | 通过观察乙二醛染素养在鼠血及组织中谷胱鞭挞 肽过氧化物酶（ＧＳＨ－Ｐｘ）活力的变化，探讨了乙二醛对抗氧化酶活力的影响。经气管灌注法对大鼠染毒，测定全血和组织中ＧＳＨ－ＰｘＰ的活力，结果表明在高剂量组全血ＧＳＨ－Ｐｘ活力显著低于对照组。乙二醛对全血ＧＳＨ－Ｐｘ活力的影响主要表现为降低作用，脏器中ＧＳＨ－Ｐｘ的活力变化表现为应激性增高趋势，以肾脏最为明显。
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| 关 键 词： | 乙二醛 谷胱甘肽过氧化物酶 |
Effects of Glyoxal on Activities of Anti-oxidase in Blood and Tissues of Rats |
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| Fan Laifu et al. Effects of Glyoxal on Activities of Anti-oxidase in Blood and Tissues of Rats[J]. Industrial Health and Occupational Diseases, 2000, 26(4): 207-208 |
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| Authors: | Fan Laifu et al |
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| Abstract: | Effects of glyoxal on anti oxidase in rats were studied by observing the activity changes of GSH Px in blood and tissues after exposure.Glyoxal was instilled through respiratory track.The activities of GSH Px in blood and tissues were measured.The activities of blood GSH Px of high dose group were significantly lower than that of the controls.Glyoxal exposure inhibited the GSH Px activities of blood,while the effects on tissues were not the same.An increase tendency of GSH Px activities in tissues was observed.In kidney,the increase was significant. |
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| Keywords: | Glyoxal GSH Px Rat |
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