| 氧自由基与人体纤维囊形成 |
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| 引用本文： | 陈小平,李松春.氧自由基与人体纤维囊形成[J].中国修复重建外科杂志,1996,10(1):29-31. |
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| 作者姓名： | 陈小平 李松春 |
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| 作者单位： | 杭州整形医院，浙江大学电子自旋共振检测室 |
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| 摘 要： | 经动物实验研究，已证明硅橡胶囊植入体内形成的纤维囊与氧自由基有关，但在人体内的研究尚少。采用电子自旋共振（ｅｌｅｃｔｒｏｎｓｐｉｎｒｅｓｏｎａｎｃｅ，ＥＳＲ）技术，对７枚人体硅胶囊隆乳术后形成的纤维囊进行了检测，同时对纤维囊的组织病理学特征进行了观察。结果发现，纤维囊内有大量氧自由基产生，其病理改变主要为大量炎性细胞浸润和胶原沉积。表明人体内纤维囊的形成与氧自由基有关。应用氧自由基清除剂，可使增厚的纤维囊变薄
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| 关 键 词： | 氧自由基 电子自旋共振 人体纤维囊 组织病理学 |
OXYGEN FREE RADICAL AND HUMAN FIBROUS CAPSULE |
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| /Chen Xiaoping,Li Songchun,Song Jianliang et al.OXYGEN FREE RADICAL AND HUMAN FIBROUS CAPSULE[J].Chinese Journal of Reparative and Reconstructive Surgery,1996,10(1):29-31. |
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| Authors: | /Chen Xiaoping Li Songchun Song Jianliang |
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| Institution: | /Chen Xiaoping,Li Songchun,Song Jianliang et al. Department of Plastic Surgery,Hangzhou Plastic Surgical Hospital,Hangzhou 310014 |
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| Abstract: | The specimens were obtained from 7 fibrous capsules two years after mammoplasty with silicone prosthesis, and were examined by electron spin resonance (ESR) and microscope. The result showed that a marked quantities of oxygen free radical existed in the capsules and that the main pathological change was the infiltration of massive inflammatory cells and deposition of collagen. It was suggested that the fibrous capsule formation was concerned with the oxygen free radical. The origin of the oxygen free radical in mammoplasty with slicone was also discussed. |
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| Keywords: | Oxygen free radical Electron spin resonance Human fibrous capsule Histopathology |
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