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脑卒中患者同型半胱氨酸、抗心磷脂抗体的检测及探讨
引用本文:吴坚洪,许献文,黄敦燕,邝桂婵,王孔专,吴雪梅.脑卒中患者同型半胱氨酸、抗心磷脂抗体的检测及探讨[J].吉林医学,2014(9):1804-1805.
作者姓名:吴坚洪  许献文  黄敦燕  邝桂婵  王孔专  吴雪梅
作者单位:南海区第五人民医院检验科;南海区第五人民医院ICU
摘    要:目的:研究和探讨同型半胱氨酸、抗心磷脂抗体与脑卒中的关系,为预防和治疗脑卒中提供依据。方法:选择127例脑卒中患者为研究对象,根据患者病情分为脑梗死组与脑出血组,对同型半胱氨酸、抗心磷脂抗体水平进行测定和比较。结果:脑出血组同型半胱氨酸为(24.77±12.72)μmol/L,脑梗死组同型半胱氨酸为(20.77±11.75)μmol/L均明显高于健康对照组的(9.82±2.53)μmol/L。脑梗死组患者抗心磷脂抗体阳性率为30.11%,与脑出血组患者抗心磷脂抗体阳性率8.82%比较,差异有统计学意义(P<0.05)。结论:脑卒中患者的同型半胱氨酸、抗心磷脂抗体与患者脑梗死和脑出血发病存在密切关联,及早进行同型半胱氨酸、抗心磷脂抗体检查对于预防和治疗脑卒中具有积极意义。

关 键 词:脑卒中  同型半胱氨酸  抗心磷脂抗体

Stroke patients homocysteine,anticardiolipin antibodies and to explore
Institution:WU Jian-hong;XU Xian-wen;HUANG Dun-yan;Department of clinical laboratory,The Fifth people’s Hospital of Nanhai;ICU,The Fifth people’s Hospital of Nanhai;
Abstract:Objective To study and explore homocysteine,anticardiolipin antibodies and stroke relationship for the prevention and treatment of stroke to provide evidence.Methods were treated 127 cases of stroke patients for the study,based on the patient' s condition into cerebral infarction and cerebral hemorrhage group to homocysteine,anticardiolipin antibody levels were measured and compared.Results Cerebral hemorrhage group homocysteine was (24.77 ±12.72)μmol/L,homocysteine cerebral infarction group was (20.77 ± 11.75)μ mol/L were significantly higher than the control group,(9.82 ± 2.53) μ mol/L.Cerebral infarction patients anticardiolipin antibody positive rate was 30.11% in patients with cerebral hemorrhage anticardiolipin antibody positive rate 8.82%,the difference was statistically significant(P 〈 0.05).Conclusion Patients with Stroke homocysteine,anticardiolipin antibodies with cerebral infarction and cerebral hemorrhage patients are closely related,early homocysteine,anticardiolipin antibody test for the prevention and treatment of stroke has positive significance.
Keywords:Stroke  Homocysteine  Anticardiolipin antibodies
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