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前列壮阳胶囊的提取工艺研究
引用本文:孟样凤,崔曼丽,端木庆崇. 前列壮阳胶囊的提取工艺研究[J]. 黑龙江医药, 2009, 22(3): 327-329
作者姓名:孟样凤  崔曼丽  端木庆崇
作者单位:黑龙江天宏药业有限公司,哈尔滨,150025;黑龙江天宏药业有限公司,哈尔滨,150025;黑龙江天宏药业有限公司,哈尔滨,150025
摘    要:目的:优选前列壮阳胶囊提取工艺的最佳条件,以保证临床用药的安全、有效。方法:以方中君药金钱草、淫羊藿和菟丝子的主要有效成分总黄酮为指标,用正交试验方法对前列壮阳胶囊的制备工艺进行筛选。结果:确定前列壮阳胶囊最佳提取工艺为:将金钱草等十味药材加水煎煮二次,第一次加水8倍量,浸泡1小时,煎煮1小时,第二次加水6倍量,继续煎煮1小时,合并煎液,滤过,滤液减压浓缩至相对密度为1.30(80℃)的浸膏,备用。结论:此工艺流程可直接应用于工业大生产。

关 键 词:前列壮阳胶囊  提取工艺  正交试验

Study on Extract Technology of Qianlie Zhuangyang capsules
Affiliation:Meng Xiangfeng ,et of (Heilongjiang Timehome Pharmaceutical Ca., Ltd(150025, Harbin)
Abstract:Objective: To optimize extract technology of Qianlie Zhuangyang capsules, to assure security and effective. Methods: Select the extract technology of Qianlie Zhuangyang capsule by Orthogonal Test techniques, the total flavone of Lysimachia christinae, Epimedium and Cuscuta chinensis Lam is target. Results: Qianlie Zhuangyang capsule extract technology program : Lysimachia christinae and other ingredients, boiling twice by water, for the first time adds water 8 time of quantities ,soaking 1hour, boiling 1 hours,for the second time adds water 6 time of quantities, boiling 1 hours again , Merge solution, Filtration .The filtrate was concentrated to the relative density of 1.30(80℃) of the extract by reduced pressure, prepare later to use. Conclusion: This technical process is suitable for large scale production.
Keywords:Qianlie Zhuangyang capsule  Extraction technology  Orthogonal Test
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