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Acid catalyzed hydrolysis of a series of zopiclone analogues |
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| Authors: | M Largeron M B Fleury |
| Affiliation: | Laboratoire de Chimie Analytique, U.A. 484 au C.N.R.S., Faculté de Pharmacie, Paris, France. |
| Abstract: | The pKa values of acid-base equilibria involved in the protonation of zopiclone and analogues are determined by UV-visible absorption spectrometry and pH-metry. Hydrogen ion catalysis is evidenced in the carbamate hydrolysis. |
| Keywords: | |