CHROMOSOMAL ABNORMALITIES AND POLYMORPHISMS IN MEXICAN INFERTILE MEN |
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| Authors: | E. I. CORTÉS-GUTIÉRREZ R. M. CERDA-FLORES M. I. DÁVILA-RODRÍGUEZ R. HERNÁNDEZ-HERRERA J. VARGAS-VILLARREAL C. H. LEAL-GARZA |
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| Affiliation: | 1. Genetics Division, Centro de Investigación Biomédica del Noreste (CIBIN), Instituto Mexicano del Seguro Social (IMSS), Mexico;2. Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León (UANL), Mexico;3. Facultad de Enfermería, UANL, Mexico;4. Hospital Regional de Especialidades No. 23, Ignacio Morones Prieto, IMSS, Mexico;5. Cellular and Molecular Biology Division, CIBIN, IMSS, Mexico |
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| Abstract: | A cross-sectional study was conducted to estimate the prevalence of chromosome abnormalities and normal variable chromosome features (polymorphisms) in infertile men from northeastern Mexico. Karyotyping was carried out in 326 men with diagnosis of infertility. The sperm counts showed 204 patients with oligozoospermia, 87 with azoospermia and 35 normozoospermia. Five patients with oligozoospemia and two with azoospermia presented chromosome abnormalities. Nonzoospermic men did not show chromosomal abnormalities. Polymorphisms of heterochromatin and satellite length showed a significant increased in oligozoospermic and azoospermic men with respect to normozoospermic men, respectively. This study reports the prevalence of chromosome abnormalities, polymorphisms of heterochromatin length, and polymorphisms in satellites in Mexican infertile men. The prevalence in this study was similar to other studies in world literature. |
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| Keywords: | chromosome infertility Mexico polymorphism |
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