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Plasmatic β-endorphin levels and thalamic surgery for pain |
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| Authors: | José A Lopez Fernando Perán Alberto Altuzarra Federico Carrido Ventura Arjona |
| Institution: | 1. Servicio Regional de Neurocirugia, Centro de Traumatología, Cra. de laen s/n., Granada, Spain;2. servicio de Análisis Clínicos, Ciudad Sanitaria “Virgen de las Nieves”, Avda. Calvo Sotelo 700, Granada, Spain |
| Abstract: | Plasma B-endorphin levels were found to be significantly lower in patients suffering from chronic pain of malignant etiology than in a control group. After a bilateral stereotactic cry oth al am oto my in Centrum Medianum and Par afasci cu I aris nuclei, a good clinical result and a significant increase in plasma B-endorphin levels were obtained. |
| Keywords: | Opioid peptides intractable pain stereotactic thalamotomy Centrum Medianum-Parafascicularis complex |