| Diagnosis and Treatment of Chronic Cough due to Gastroesophageal Reflux Disease |
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| 引用本文： | 黄漾,邱忠民. Diagnosis and Treatment of Chronic Cough due to Gastroesophageal Reflux Disease[J]. 中国医学文摘:外科学分册英文版, 2007, 16(1): 77-82 |
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| 作者姓名： | 黄漾 邱忠民 |
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| 作者单位： | Department of Respiratory, Tongji Hospital, Tongji University, Shanghai200065, China |
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| 摘 要： | Gastroesophageal reflux disease is one of most common causes of chronic cough.Medical history offers few clues as to the cause of cough induced by this disease.24-h esophageal ph monitoring is considered as the most sensitive and specific test for the diagnosis.When it is unavailable or unsuitable,upper gastrointestinal endoscopy and barium esophagography can be used as an alternative examination.Combined multichannel intraluminal impedance and pH testing is promising because of its ability to detect nonacid reflux as well as acid reflux.Empiric therapy trial is a simple and cheap way to identify suspected patients.Drug therapy is effective in most of the patients,in which proton pump inhibitors is the most powerful.Antireflux surgery is the last choice,used only when intensive drug therapy fails.The definitive diagnosis of cough due to gastroesophageal reflux disease can be established only after cough improves or completely disappears with antireflux therapy.
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| 关 键 词： | 诊断方法 治疗 慢性咳嗽 胃食管反流 |
Diagnosis and Treatment of Chronic Cough due to Gastroesophageal Reflux Disease |
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| Huang Yang ,Qiu Zhongrnin. Diagnosis and Treatment of Chronic Cough due to Gastroesophageal Reflux Disease[J]. China Medical Abstracts, 2007, 16(1): 77-82 |
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| Authors: | Huang Yang Qiu Zhongrnin |
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| Affiliation: | Department of Respiratory, Tongji Hospital, Tongji University, Shanghai200065, China |
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| Abstract: | Gastroesophageal reflux disease is one of most common causes of chronic cough. Medical history offers few clues as to the cause of cough induced by this disease. 24-h esophageal ph monitoring is considered as the most sensitive and specific test for the diagnosis. When it is unavailable or unsuitable, upper gastrointestinal endoscopy and barium esophagography can be used as an alternative examination. Combined multichannel intraluminal impedance and pH testing is promising because of its ability to detect non-acid reflux as well as acid reflux. Empiric therapy trial is a simple and cheap way to identify suspected patients. Drug therapy is effective in most of the patients, in which proton pump inhibitors is the most powerful. Antireflux surgery is the last choice,used only when intensive drug therapy fails. The definitive diagnosis of cough due to gastroesophageal reflux disease can be established only after cough improves or cc.npletely disappears with antireflux therapy. |
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| Keywords: | Gastroesophageal reflux disease Chronic cough Diagnosis Treatment |
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