| 肝病患者血浆GMP-140检测及临床意义 |
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| 引用本文： | 杨清 白杨 霍德胜 柳忠辉. 肝病患者血浆GMP-140检测及临床意义[J]. 吉林医学, 2006, 27(7): 737-737 |
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| 作者姓名： | 杨清 白杨 霍德胜 柳忠辉 |
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| 作者单位： | [1]吉林大学第一医院,吉林长春130021 [2]吉林大学基础医学院,吉林长春130021 |
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| 摘 要： | 目的:探讨血小板α-颗粒膜蛋白(GMP-140)在肝病诊断中的意义。方法:采用酶联免疫吸附实验(ELISA)检测肝病患者血浆GMP-140含量。结果:3组肝病患者GMP-140含量与正常对照组比较均显著升高(P<0.01)。丙型、乙型肝炎相比无明显差异(P>0.05)。肝癌患者血浆GMP-140较丙型、乙型肝炎显著增高(P<0.05;P<0.01)。结论:检测肝病患者GMP-140可做为肝病患者,尤其是肝癌患者纤溶亢进及评估预后的指标。
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| 关 键 词： | 肝病患者 血小板α-颗粒膜蛋白 |
| 文章编号： | 1004-0412（2006）07-737-01 |
| 收稿时间： | 2005-12-12 |
| 修稿时间： | 2005-12-12 |
The clinic significance of detecting blood plasma GMP-140 in liverish patients |
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| YANG Qing,BAl Yang,HUO De-sheng. The clinic significance of detecting blood plasma GMP-140 in liverish patients[J]. Jilin Medical Journal, 2006, 27(7): 737-737 |
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| Authors: | YANG Qing BAl Yang HUO De-sheng |
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| Affiliation: | The First Hospital of Jilin University, Changchun 130021,China;2.The Basic Medical Academy of Jilin University ,Changchun 130021,China |
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| Abstract: | Objective To discuss the diagnosis significance of blood platelet α-granule membrane protein(GMP-140)in liver disease. Method The content of blood plasma GMP-14 in liverish patients were detected by enzyme linked immunosorbent assay (ELISA). Results The content of GMP-140 in three group liverish patients were significantly higher than those in controls(P<0.01).The content were not significantly different between hepatitis B virus and hepatitis C virus patients. The content of GMP-140 were significantly higher in liver cancer patients than those in hepatitis B virus and hepatitis C virus patients(P<0.05;P<0.01). Conclusion Detecting the content of liverish patients GMP-140 can be a guideline of sthenic fibrinolysis in liverish patients especially liver cancer patients and to evaluate the prognosis. |
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| Keywords: | Liverish patients Blood platelet a-granule membrane protein |
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