Modifiable risk factors for adherence to adjuvant endocrine therapy among breast cancer patients |
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Authors: | Kimberly R. Jacob Arriola,Tamara A. Mason,Kari Ann Bannon,Carol Holmes,Cecil Lamonte Powell,Kandra Horne,Ruth O&rsquo Regan |
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Affiliation: | 1. Rollins School of Public Health of Emory University, Department of Behavioral Sciences and Health Education, Atlanta, USA;2. Emory University School of Medicine and Winship Cancer Institute, Atlanta, USA |
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Abstract: | ObjectiveBreast cancer incidence and mortality are declining due to improvements in early detection and treatment. One advance in treatment is the development of adjuvant endocrine therapy (AET) for women with hormone receptor positive breast cancer. Despite strong evidence linking AET to better health outcomes, AET adherence continues to be suboptimal. This study tests the hypothesis that patient beliefs about medication mediate the relationship between frequency of physician communication and AET adherence.MethodsThis cross-sectional study utilizes data from patient self-report and medical chart abstraction (N = 200). Survey measures included frequency of physician communication, patient beliefs about medicine, AET adherence, and demographic characteristics.ResultsNecessity beliefs mediated the relationship between frequency of physician communication and medication adherence (necessity beliefs β = .18, p < .05; physician communication β = .13, p > .05). There was no evidence of medication concerns mediating the relationship between frequency of physician communication and medication adherence.ConclusionMore frequent physician communication that shapes what patients believe about AET importance may be associated with greater AET adherence; however, frequent physician communication that shapes patient concerns about side effects may not be associated with greater AET adherence.Practice implicationsResearch is needed to enhance understanding of the type of physician communication that is most consistently associated with patient beliefs about medication and AET adherence. |
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Keywords: | Breast cancer Adjuvant endocrine therapy Medication beliefs Adherence |
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