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Nephroblastoma and end-stage renal failure with bilateral cystic kidneys |
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| Authors: | Randall D. Craver Hernan Correa Jean G. Hollowell Rajasekharan P. Warrier |
| Affiliation: | (1) Department of Pathology, Louisiana State University School of Medicine, 1901 Perdido Street, 70112-1393 New Orleans, Louisiana, USA;(2) Department of Pediatrics, Louisiana State University School of Medicine, 1901 Perdido Street, 70112-1393 New Orleans, Luisiana, USA;(3) Department of Urology, Tulane University School of Medicine, New Orleans, Louisiana, USA;(4) New Orleans Children's Hospital, New Orleans, Louisiana, USA |
| Abstract: | A child of 10 years 5 months presenting with chronic renal failure had bilateral cystic kidneys. Biopsy of a right lower-pole solid mass revealed nephroblastoma. At bilateral nephrectomy, both kidneys were both replaced by variable-sized cysts with a unifocal nephroblastoma on the right. Renal failure with nephroblastoma is uncommon and is usually either a manifestation of the Drash syndrome or a complication of chemotherapy. The need to assess both kidneys in a child with any other renal abnormality in addition to a renal mass should always be considered. |
| Keywords: | Cystic kidneys Nephroblastoma Renal failure |
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