多项血液指标在冠心病诊断及预后判断中的价值

目的探讨红细胞分布宽度(RDW)、血小板分布宽度(PDW)、超敏心肌肌钙蛋白T(hs-cTnT)、超敏C反应蛋白(hs-CRP)、同型半胱氨酸(Hcy)和总胆红素在冠心病诊断及预后判断中的价值。方法广西壮族自治区桂林市中西医结合医院2011年8月至2012年12月住院的112例冠心病患者,根据病情分为心绞痛组(AP组,50例)和急性心肌梗死组(AMI组,62例),进行RDW、PDW、hs-cTnT、hs-CRP、Hcy和总胆红素的检测,并与同期健康体检者进行比较。结果 AMI组hs-cTnT、hs-CRP及Hcy水平分别为(2.957±1.963)μg/L、(5.36±1.28)mg/L、(60.05±15.39)μmol/L,与AP组及健康对照组比较明显升高(均P<0.05)。出院前1d,112例冠心病患者的RDW、hs-cTnT、hs-CRP、Hcy分别为13.15%±0.71%、(0.008±0.002)μg/L、(2.95±0.78)mg/L、(16.77±3.53)μmol/L,较入院时明显降低(均P<0.01)。结论对冠心病患者及时进行RDW、hs-cTnT、hs-CRP、Hcy和总胆红素的检测,在冠心病诊断及预后判断中具有重要意义。

The value of blood indicators in the diagnosis and prognosis of coronary heart disease

Objective To explore the value of red blood cell distribution width（RDW）,platelet distribution width（PDW）,high-sensitivity cardiac troponin T（hs-cTnT）,high sensitive C reactive protein（hs-CRP）,homocysteine（Hcy）and total bilirubin in the diagnosis and prognosis of coronary heart disease.Methods 112 patients with coronary heart disease in Hospitals of Traditional Chinese and Western Medicine in Guilin City from August 2011 to December 2012 were devided into angina pectoris group（group AP,50 cases） and acute myocardial infarction group（group AMI,62 cases）,in which RDW,PDW,hs-cTnT,hs-CRP,Hcy and total bilirubin were detected and compared with healthy control group.Results The hs-cTnT,hs-CRP and Hcy levels of group AMI were（2.957±1.963） μg/L,（5.36±1.28）mg/L,（60.05±15.39）μmol/L respectively,which were increased significantly than those of the group AP and the healthy control group（P0.01 or P0.05）.RDW,hs-cTnT,hs-CRP,Hcy of 112 cases of patients with coronary heart disease were 13.15%±0.71%,（0.008±0.002） μg/L,（2.95±0.78） mg/L,（16.77±3.53）μmol/L 1 d before leaving hospital,which were decreased significantly than that the day of admission（P0.01）.Conclusion It could be with great significance in the diagnosis and prognosis of coronary heart disease by detecting the RDW,hs cTnT,hs CRP,Hcy and total bilirubin in time.