The excretion and distribution of inorganic mercury in the rat as influenced by several chelating agents |
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| Authors: | B. Gabard |
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| Affiliation: | (1) Institut für Strahlenbiologie, Kernforschungszentrum Karlsruhe, Karlsruhe |
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| Abstract: | Among 15 chelating agents tested, sodium-2,3-dimercaptopropane-1-sulfonate (DMPS), 2,3-dimercaptopropanol (BAL), sodium-mercaptoethyliminodiacetate (MEIDA), and D-penicillamine (PA) exerted an influence on the excretion of Hg and its distribution in the organs. The excretion pattern, however, is different for these compounds, and, from the practical point of view, a favourable effect is exhibited only by DMPS which enhances the urinary excretion rate and lowers the Hg-concentration in all organs. |
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| Keywords: | Inorganic mercury Chelating agents Excretion Distribution Rat |
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