伴有大脑中动脉狭窄急性脑梗死患者扩容治疗及微栓子监测的研究

目的通过对伴有大脑中动脉（MCA）狭窄的急性脑梗死患者进行扩容治疗，来评价患者的预后。方法选取伴有病灶侧大脑中动脉狭窄急性脑梗死患者180例，其中扩容组89例，对照组91例。扩容组进行扩容治疗，对照组常规治疗，分别于人院时、第3天、第7天、第14天进行TCD检测狭窄MCA的微栓子的数量。14d后给予临床神经功能缺损评分，进行临床疗效比较。结果扩容组患者的显效率及总有效率均高于对照组，差异有统计学意义（P〈0．01）；扩容组的微栓子数量较对照组增多，但无统计学意义。结论扩容治疗可以改善伴有大脑中动脉狭窄急性脑梗死患者的预后。

Expansion treatment and microemboli monitoring of middle cerebral artery stenosis with acute cerebral infarction

Objective To evaluate prognosis of the patients in acute cerebral infarctions with middle cerebral artery stenosis after expansion treatment. Methods 180 patients in acute cerebral infarctions with middle cerebral artery stenosis were ehoosed in department of neurology, 89 patients were treated with volume expansion therapy, 91 pa- tients were treated with conventional therapy. Two groups were detected blood flow rate of middle cerebral artery stenosis with TCD on admission, 3 days, 7 days and 14 days, and measured the blood pressure and recorded the a- mount of mieroemboli at the same time, and measured the clinical neurologic impairment and compared therapeutic effect after 14 days. Results The total effective rate of the fluid expansion group patients was higher than that of the control group patients, that is significant（P〈0.01）. The amount of microemboli in the fluid expansion group pa- tients was much more than that in the control group patients, but that was no significant. Conclusions The volume expansion therapy can improve the patients in acute cerebral infarctions with middle cerebral artery stenosis.