玻璃体腔注射曲安奈德治疗白内障术后黄斑囊样水肿疗效观察

目的:观察玻璃体腔注射曲安奈德(triamcinoloneacetonide,TA)治疗白内障术后黄斑囊样水肿(cystoid macular ede-ma,CME)的疗效。方法:对21例22眼经间接检眼镜、荧光素眼底血管造影(FFA)以及光学相干断层扫描(OCT)检查确诊的CME患者行TA玻璃体腔注射,治疗后随访0.5a,对比分析术前术后不同时期的视力、眼底、FFA表现,观察OCT显示黄斑水肿高度。结果:术前视力平均0.25±0.23,术后3mo平均0.58±0.27,差异有显著性(P<0.01);经OCT随访检查,术后所有病例患眼黄斑中心凹厚度均有下降,术前平均为(482.37±102.54)μm,术后3mo平均为(205.46±113.35)μm,差异有显著性(P<0.01)。结论:玻璃体腔注射TA是一种安全有效的治疗白内障术后黄斑囊样水肿的方法。

Intravitreous injection of triamcinolone ace-tonide for cystoid macular edema after cataract surgery

·AIM:To observe therapeutic effect of intravitreous injection of triamcinolone acetonide(TA)for cystoid macular edema(CME)after cataract surgery..METHODS:TA was injected intravitreally in 22 eyes of 21 patients with CME determined by indirect ophthalmo-scope,fundus fluorescence angiography(FFA)and optical coherence tomography(OCT).The visual acuity,fundus findings,FFA manifestation and macular thickness under OCT were recorded and analyzed prior to the operation and at different time points after the operation.Follow-up time was 6 months..RESULTS:The average visual acuity was 0.25±0.23 before the operation,whereas it was 0.58±0.27 at 3 months after the operation.There was significant difference statistically(P<0.01).Through OCT follow-up,the macular thickness of operated eyes in all cases were reduced from(482.37±102.54)μm preoperatively to(205.46±113.35)μm postoperatively.There was statisti-cally significant difference(P<0.01)..CONCLUSION:Intravitreal injection of TA is a safe and effective method for the treatment of cystoid macular edema after cataract surgery..