抗敏口服液研制与临床实验研究

中药抗敏口服液是以祖国传统中医药理论为立论组方依据，以酸甘止痒合剂临床应用研究取得良好效果的前期工作为基础，精选药物，科学组方，制成的纯天然抗过敏口服制剂．其制备工艺科学简便，所批质量标准能控制制剂质量．药效学实验表明：抗敏口服液具有抗刊型、I型变态反应作用和抗炎解热作用．毒理学试验研究表明：该制剂安全可靠，对大鼠心、肝、脾、肺、肾、脑等重要器官均无损害作用，对大鼠生长发育无影响。临床应用结果提示；中药抗敏口服液治疗荨麻疹、丘疹性等麻疹、过敏性鼻炎及小儿哮喘等过敏性疾病的痊愈（临床控制）率为64．9％，痊愈加显效率为86．8％。总有效率为93．2％．副作用小和无中枢镇静作用方面可与总斯敏媲美，且其复发率更低．表明抗敏口服液这一中药新型液体口服制剂具有疗效好、作用快、副作用小及治愈后复发率低等善治慢性、难治之症的特色，是一种无镇静和嗜睡到作用的纯天然抗过敏新药。

THE STUDY OF PREPARATION AND CLINIC EXPERIMENT OF ANTI-ALLERGY ORAL LIQUID

Anti-allergy oral liquid was a pure natural preparation made of carefully choice herbalmedicines based on the theory of Chinese Traditional Medicine and the successful Clinical study ofSuangan Ziyang mixture.Its tecgbnologt was simple and scientific Its standard of quality can be controled Pharmacodyna-mic Studies confirmed its anti-allerg,anti-inflammation,and fever-reducing effects. Toxicological ex-periments show that this preparation is safe and relable. and no intoxicational patological changes wereobserved in unimals' heart,liver,spleen, lung,kidney and brain by light microscope. The drug has noinhibition on the animals' growth and development. The clinical resesarch shows that the cure rate ofthe allergoese (urticaria, urticaria papulose,allergic rhinitis and childish asthma) treated with anti-aLlergy oral liquid is 64. 9% the curative and marked effective rate is 86. 8%,the total effective rate is93. 2%;anti-allergy oral liquid has quick curative effect and low rate of recurrence. It is free fromsuch side-effects as lethargy,dizziness and dry m0uth- The result of random comparison shows that inthe treatment effect Anti-allergy oral liquid is a rival of Astemizole