中西医结合治疗中重度癌痛25例临床观察

目的:观察中药外用联合口服奥施康定治疗癌痛的临床疗效。方法:将50例患者采用区组随机化方法随机分为治疗组(25例)和对照组(25例);2组均按滴定剂量给予奥施康定,治疗组同时用中药药液擦于痛处皮肤,3~5次/d,3周为1个疗程。观察2组止痛效果、奥施康定用量以及2组便秘情况。结果:治疗组疼痛控制明显优于对照组(P0.025),奥施康定用量较对照组明显减少(P0.005),对照组便秘发生率高于治疗组(P0.05)。结论:中西医结合控制癌性疼痛,提高疗效,减少便秘的发生。

Observation on Integrated Traditional Chinese and Western Medicine in Treating 25 Cases of Medium and Severe Cancer Induced Pain

To observe the effects of external application of traditional Chinese medicine combined with oral administration of oxycodone for the treatment of medium and severe cancer induced pain.Methods：Fifty patients with cancer pain were randomly divided into treatment group （n=25 ）and control group （n=25 ）by the method of block randomization.Both groups gave patients oxycodone according to the dosage titration,and the treatment group applied traditional Chinese medicine （TCM）solution to the raw skin at the same time,3 to 5 times a day for 3 weeks.The effect in the two groups,the dosage of oxycodone and constipation condition were observed.Results：The pain control of the treatment group was obviously better than that of the control group （P〈0.05 ）;the dosage of oxycontin in treatment group was decreased significantly （P〈0.05 ）compared with the control group;the incidence rate of constipation of the control group was higher than that of the treatment group （P〈0.05 ）.Conclusion：Integrated traditional Chinese and western medicine in controlling cancer induced pain can increase curative effect and reduce the occurrence of constipation.