超敏C反应蛋白变化与缺血性脑卒中的研究 |
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引用本文: | 齐英斌,白春艳,周艳,刘敏,马爽,孙宏侠,江新梅.超敏C反应蛋白变化与缺血性脑卒中的研究[J].中国实验诊断学,2009,13(9):1188-1189. |
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作者姓名: | 齐英斌 白春艳 周艳 刘敏 马爽 孙宏侠 江新梅 |
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作者单位: | 1. 吉林省人民医院,吉林,长春130021 2. 吉林大学第一临床医院 |
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摘 要: | 目的探讨超敏C反应蛋白(hs—CRP)在缺血性脑卒中发病过程中的变化及其与预后的关系。方法采用免疫比浊法动态检测82例缺血性脑卒中患者及20名正常对照者的hs—CRP变化,分析hs—CRP与梗死面积大小,病情和预后的相关性。结果缺血性脑卒中患者hs-CRP水平与病情及预后关系密切,其中大面积梗死组hs-CRP升高,持续时间长,神经功能缺损程度越重,预后越差;与中、小面积梗死组比较,差异有非常显著统计学意义(P〈0.01)。结论缺血性卒中患者hs-CRP水平可作为判断病情及预后的客观指标,hs—CRP越高,持续时间越长,预后越差。
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关 键 词: | 超敏C反应蛋白 缺血性脑卒中 |
Research of relationship between the kinetic changes of high-sensitive C-reactive protein level and in patients with Ischemic Stroke |
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Institution: | QI Ying-bin, BM Chun-yan, ZHOU Yah, et al. ( Jilin Provincial ltospital , Changchun 130021, China ) |
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Abstract: | Objective To investigate the association between the kinetic changes of high-sensitive C-reactive protein level and prognosis during the progression of Isehemic Stroke. Methods High-sensitive C-reactive protein levels of 82 patients with Ischemic Stroke and 20 healthy volunteers served as a control group were tested with immtmoturbidimctric assay and were analyzed whether to correlate with severity and outcome after Isehemie Stroke. Results There was the significant correlation between high-sensitive C-reactive protein levels and severity, prognosis in patients with Isehemic Stroke. High-sensitive C-reactive protein levels in larger Infarction group was higher and lasted longer than that in middle and smaller infarction groups, the difference was Statistically significant obviously (P 〈 0.01). High levels of high-sensitive C-reactive protein inlarger infarction group indicated more severe neurologic functional impairment and worse prognosis. Conclusion High-sensitive C-reactive protein is as ignificant risk factor for severity and prognos is in patients with Ischemie Stroke. If high-sensitive C-reactive protein levels are high and last long, the patients with Isehemic Stroke have unfavourable prognosis. |
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Keywords: | high-sensitive C-reactiveprotein ischemic stroke |
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