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诺氟沙星注射液动物体内抗菌实验研究
引用本文:姜宁,刘玲,温操琼,刘先觉.诺氟沙星注射液动物体内抗菌实验研究[J].中国药房,2002,13(5):267-268.
作者姓名:姜宁  刘玲  温操琼  刘先觉
作者单位:重庆市急救医疗中心药剂科,重庆市400014
摘    要:目的 :研究诺氟沙星注射液对动物的抗菌作用。方法 :将大肠杆菌及金葡菌悬液分别注射到小白鼠腹腔和家兔体内造成感染后 ,分成治疗组、预防组和对照组进行观察。结果 :两种细菌使对照组小白鼠在24h内全部死亡 ,治疗组、预防组则全部存活 ;家兔作类似实验亦有同样的效果。结论 :大肠杆菌及金葡菌感染动物应用诺氟沙星注射液具有明显的预防和治疗作用

关 键 词:诺氟沙星注射液  体内抗菌  实验研究
文章编号:1001-0408(2002)05-0267-02
修稿时间:2002年1月29日

Experimental Study on the in Vivo Antibacterial Effects of Norfloxacin Injection in Animals
JIANG Ning,LIU Ling,WEN Caoqiong,LIU Xianjue.Experimental Study on the in Vivo Antibacterial Effects of Norfloxacin Injection in Animals[J].China Pharmacy,2002,13(5):267-268.
Authors:JIANG Ning  LIU Ling  WEN Caoqiong  LIU Xianjue
Abstract:OBJECTIVE:To study the in vivo antibacterial effects of Norfloxacin injection in animals.METHODS:After infecting the animals by injection of Escherichia coli and Staphylococcus aureus suspension into the mice's abdominal cavity and rabbit's body,the animals were divided into therapy,prophylaxis and control groups to observe the effect of Norfloxacin.RESU-LTS:All mice of control group died within 24 hours after the injection of bacteria while those of the therapy and prophylaxis groups survived.The results of experiment on rabbits were similar to those on mice.CONCLUSION:The results show that Norfloxacin injection has obvious therapeutic and prophylactic effects on infections induced by E.coli and Staphylococcus aureus.
Keywords:Norfloxacin injection  in vivo antibacterial action  experimental study  
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