| Sonic hedgehog signaling during nervous system development*☆ |
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| 作者姓名： | Qin Yang Peng Xie |
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| 基金项目： | Supported by： the Science Foundation of Education Committee of Chongqing City, No. KJ070310 |
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| 摘 要： | The Hedgehog signaling pathway plays a key role in embryonic development and organ formation. Sonic hedgehog signaling participates in nervous system development, regulates proliferation and differentiation of neural stem cells, controls growth and targeting of axons, and contributes to specialization of oligodendrocytes. For further studies of the Sonic hedgehog signaling pathway and for the development of new drugs in the treatment of nervous system diseases, it is beneficial to understand these mechanisms.
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| 关 键 词： | 猬 神经紧张系统 胚胎发育 器官形成 |
| 收稿时间： | 4/1/2008 12:00:00 AM |
| 修稿时间： | 5/6/2008 12:00:00 AM |
Sonic hedgehog signaling during nervous system development |
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| Qin Yang,Peng Xie.Sonic hedgehog signaling during nervous system development[J].Neural Regeneration Research,2008,3(7):782-785. |
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| Authors: | Qin Yang and Peng Xie |
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| Institution: | Department of Neurology, First Affiliated Hospital, Chongqing Medical University;Department of Neurology, First Affiliated Hospital, Chongqing Medical University |
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| Abstract: | Abstract
The Hedgehog signaling pathway plays a key role in embryonic development and organ formation. Sonic hedgehog signaling participates in nervous system development, regulates proliferation and differentiation of neural stem cells, controls growth and targeting of axons, and contributes to specialization of oligodendrocytes. For further studies of the Sonic hedgehog signaling pathway and for the development of new drugs in the treatment of nervous system diseases, it is beneficial to understand these mechanisms.
Key Words: development; nervous system; review; Sonic hedgehog |
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| Keywords: | development nervous system review Sonic hedgehog |
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