Use of botulinum toxin type A in pediatric patients with cerebral palsy: a three-center retrospective chart review |
| |
Authors: | Gormley M E Gaebler-Spira D Delgado M R |
| |
Institution: | Department of Physical Medicine and Rehabilitation, Gillette Children's Specialty Healthcare, St. Paul, MN 55101, USA. mgormley@gillettechildrens.com |
| |
Abstract: | Over the last several years, botulinum toxin type A has gained widespread use for the management of focal spasticity in children with cerebral palsy. To assess the current patterns of botulinum toxin type A use in the clinical setting, the dose, muscles injected, age at injection, and interval between injections of botulinum toxin type A treatments were examined in a retrospective chart review of children with cerebral palsy (N = 270) over a 2-year period at three major treatment centers. The average dose of botulinum toxin type A across the three centers ranged from 7.7 to 10.8 U/kg body weight, and the average total amount of botulinum toxin type A injected at a single visit ranged from 154 to 205 U. The majority of botulinum toxin type A injections were to the muscles to the lower limbs. The average age at first injection was 6.2 years, and the average interval between injections ranged from 134 to 199 days. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|