突聋预后相关因素的分析

目的：研究影响突聋预后的相关性因素。方法：对146例（167耳）突聋的临床资料进行回顾性分析，并应用SAS system计算机系统进行预后相关因素的研究。结果：年龄小于50岁、发病14d以内就诊治疗以及单耳患病的病人预后较好；伴有眩晕症状、未患病耳既往曾有感音神经性聋病史、初诊时听力损失曲线为全聋型、高频听力（4kHz及8kHz）损失较重以及高频听阈（4kHz 8kHz）大于低频（250Hz 500Hz）听阈的病人预后不佳；治疗方案的选择并不影响病人的预后；多因素分析显示8kHz的听阈水平与预后关系最为密切，其它依次为眩晕、4kHz听阈、就诊时间、损失类型及未患病耳的既往病史。结论：从单、多因素分析的结果可以看出，突聋研究应采用多因素逐步分析的方法进行分析，以使预后和疗效评估更具准确性和客观性。

Sudden sensorineural hearing loss: statistical analysis of relevant factors with prognosis

Objective To further investigate relevant factors with the prognosis of sudden sensorineural hearing loss (SSHL). Methods A total of 146 cases (167 ears) were studied by SAS system on factors relevant with prognosis. Results Those who were younger than 50 and paid the initial visit within 14 days after the onset of unilateral SSHL indicated a good prognosis. The presence of vertigo, having a sensorineural hearing less history, an initial audiometric curve of complete deafness and a worse high-frequency (4 kHz and 8 kHz) hearing level, a difference between high (4 kHz + 8 kHz) and low (250 Hz + 500 Hz) frequency indicated a bad prognosis. The prognosis was not influenced by the medicine or the duration of treatment. Multivariance analysis showed that the 8 kHz hearing level at the initial visit influenced prognosis most, and followed by the presence of vertigo, the 4 kHz hearing level, the initial visit, the type of the audiometric curve and having a sensorineural hearing loss history. Conclusion Results from statistical analysis suggested that the unification of the diagnosis and therapeutic efficiency as well as the application of the multifactor regression analysis, are essential for SSHL research.