Bone Blood Flow in Conscious Dogs at Rest and During Exercise |
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Authors: | Erik T ndevold Jens Bü low |
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Affiliation: | a Department of Orthopaedic Surgery O, Hillerad Hospital, Copenhagen, Denmarkb Institute of Medical Physiology C, University of Copenhagen, Copenhagen, Denmark |
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Abstract: | Using the microsphere technique bone blood flow was measured in different anatomical and functional regions in long bones in conscious dogs. The measurements were performed during physical exercise upon a treadmill, and the bone blood flow values were obtained as prework resting values after 1 and 2 hours of exercise and after I hour of rest.
The perfusion rates increased 50 per cent from 1.6 to 2.5 ml 100 g tissue-1 min-1 in the femoral and tibial cortical bones during work. In the cancellous bone of the femoral head an increase from 12.6 to 20.6 ml 100 g tissue-1 min-1 was found. Equal flow responses were determined in the fat-filled tibia-condylar and femoral supracondylar bone. The increase took place after 2 hours' exercise, but nonstatisti-cally verified increased perfusion was found after 1 hour's work. The alternation in bone blood flow suggests that bone has a capability of physical vasodilatation during muscular work but the flow response is slow and therefore the vasodilatation seems mediated by a metabolically induced stimulus. |
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Keywords: | bone blood flow hyperaemia microcirculation microspheres |
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