| 包膜微泡超声造影剂的研究进展 |
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| 引用本文： | 张雪娇,程永清,李丽君,王小荣. 包膜微泡超声造影剂的研究进展[J]. 中国医学影像技术, 2005, 21(5): 819-821 |
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| 作者姓名： | 张雪娇 程永清 李丽君 王小荣 |
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| 作者单位： | 1. 西北工业大学理学院应用化学系,陕西西安,710072
2. 西安交通大学第二附属医院,陕西西安,710003 |
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| 摘 要： | 越来越多的研究表明,包膜微泡造影剂以其优越的显影和携载等功能而逐渐成为造影剂发展的主流.按膜材料的不同,包膜微泡造影剂可分为白蛋白类、非离子表面活性剂类、脂质体类和多聚体类.本文主要对各类造影剂的研究状况及优缺点进行了介绍,并经过比较得出结论:多聚体是目前乃至将来造影剂研制中最有前途的包膜材料.
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| 关 键 词： | 包膜微泡 超声造影剂 白蛋白类 表面活性剂 |
| 文章编号： | 1003-3289(2005)05-0819-03 |
| 收稿时间： | 2004-11-10 |
| 修稿时间： | 2004-11-10 |
Progress of encapsulated microbubbles ultrasound contrast agent |
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| ZHANG Xue-jiao,CHENG Yong-qing,LI Li-jun and WANG Xiao-rong. Progress of encapsulated microbubbles ultrasound contrast agent[J]. Chinese Journal of Medical Imaging Technology, 2005, 21(5): 819-821 |
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| Authors: | ZHANG Xue-jiao CHENG Yong-qing LI Li-jun WANG Xiao-rong |
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| Affiliation: | Department of Applied Chemistry, Northwestern Polytechnical University, Xian 710072, China.;Department of Applied Chemistry, Northwestern Polytechnical University, Xian 710072, China.;The Second Affiliated Hospital of Xian Jiaotong University, Xian 710003, China;Department of Applied Chemistry, Northwestern Polytechnical University, Xian 710072, China. |
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| Abstract: | Previous studies indicated that encapsulated microbubbles ultrasound contrast agent has become mainstream in UCA's development because of excellent echocontrast and carrying function and so on. According to different membrane materials, Encapsulated microbubbles ultrasound contrast agent can be divided into several categories such as albumin, liposome, polymer. The research status and advantage and disadvantage of each UCA were introduced in this paper. Our conclusion is that polymer is the most promising one nowadays and in the future. |
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| Keywords: | Encapsulated microbubbles Ultrasound contrast media Harmonic Albumins surface-active agents |
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