升温输液对烧伤休克兔肠系膜微循环的影响

目的探讨升温输液对烧伤休克兔肠系膜微循环的影响。方法将30只新西兰兔随机分成两组，建立烧伤休克模型，一组采用低温（18℃）输液，另一组采用升温（37℃）输液，分别观测肠系膜微循环的变化。结果升温输液组与低温输液组相比较，肠系膜微动脉管径（AD）、微静脉管径（VD）显著增大（P〈0．001），微动脉血流速度（AFV）和微静脉血流速度（VFV）明显增快（P〈0．（105），毛细血管血流流态由线粒流变为线流。低温输液组微血管周围有渗出与出血13例，血流中发现有微小血栓8例，而升温输液组微血管周围有渗出与出血4例，血流中发现有微小血栓2例，两组比较差异均有统计学意义（P〈0．01）。结论升温输液对改善烧伤休克肠系膜微循环，并对烧伤休克所致多器官损害具有一定防治作用。

Effect of Temperature-raising Fluids Resuscitation on Mesenteric Microcirculation in Burn Shock Rabbits

Objective To study effect of temperature - raising fluid resuscitation on mesenteric microcirculation in burn shock rabbits. Methods 30 rabbits were randomly divided into two groups, burn shock model was established, group Ⅰ was subject to resuscitation of low temperature fluid（ 18℃）. Group Ⅱ was subject to resuscitation of temperature -raising fluid（ 37℃）.. Mesenteric microcirculation was observed by AX - 70 poly - position microcirculation instrument. Results Compared with the groupI, the mesentery microvascular calibers and flow velocity of the group Ⅱ were significantly increased; The hemodynamics changed from line speed state to particle speed state. In group Ⅰ , exudation and hemorrhage were found in 13 cases and microthomb were found in 8 cases. However, In group Ⅱ, exudation and hemorrhage were found in 4 cases and microthombs were found in 2 cases. There is significant difference between the two groups. （ P 〈 0.01）. Conclusion resuscitation of temperature - raising fluid may play a role in the improvement of circulation and acid - base balance, it can prevent muhiple organ injury after burn shock.