| Abstract: | There has been concern that vasectomy may have an adverse effect on the endocrine function of the testes and that it may cause immunological sensitization of the male to his own spermatozoa. Studies have indicated no deleterious effect on endocrine function, but there is some evidence of potential immunological damage to spermatozoa. Either vasectomy or testicular biopsy may result in immunity to spermatozoa as a result of disturbances to the barrier that sequesters the spermatozoa. Autoallergic orchitis may also occur. Studies have demonstrated that vasectomy or a preexisting state of autoimmunity to spermatozoa during testicular or epididymal surgery, trauma, or infection may precipitate a painful orchitis. |
