| 反相微乳液法制备纳米四氧化三铁颗粒 |
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| 引用本文： | 周孙英,林晨,芮兴. 反相微乳液法制备纳米四氧化三铁颗粒[J]. 福建医科大学学报, 2009, 43(2) |
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| 作者姓名： | 周孙英 林晨 芮兴 |
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| 作者单位： | 1. 福建医科大学,药学院
2. 福建医科大学 |
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| 基金项目： | 福建省教育厅资助省属高校项目 |
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| 摘 要： | 目的 通过反相微乳液法制备纳米四氧化三铁(Fe3O4).方法 通过拟三角相图,确定环已烷、Triton X-100、正丁醇及水4组分体系的油包水型微乳液,电导率测定及染料扩散法判断体系为油包水(W/O)型反相微乳.利用该微乳液的"微型水池"制备了纳米级Fe3O4黑色颗粒,优化各反应物量的比例.通过红外谱图、电子扫描电镜、元素分析对所制备的Fe3O4纳米颗粒进行了表征.结果 确定拟三角相图中微乳液的区域,得到最适组分比例.当各反应物物质的量的比例n(Fe3+)∶n(Fe2+)∶n(OH-)=3∶2∶24时得到纯的Fe3O4黑色粉末.扫描电镜图显示实验结果的Fe3O4粒径<100 nm.结论 本实验配制了正已烷、Triton X-100、正丁醇、水组分体系反相微乳,并通过该体系制备了纳米Fe3O4.
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| 关 键 词： | 迟效制剂 乳状剂 磁力学 纳米技术 药物载体 四氧化三铁 |
Preparation of Magnetic Fe_3O_4 Nano-particles via Reverse Microemulsion |
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| ZHOU Sunying,LIN Chen,RUI Xing. Preparation of Magnetic Fe_3O_4 Nano-particles via Reverse Microemulsion[J]. Journal of Fujian Medical University, 2009, 43(2) |
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| Authors: | ZHOU Sunying LIN Chen RUI Xing |
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| Affiliation: | ZHOU Sunying1,LIN Chen1,RUI Xin2 1. School of Pharmacy,Fujian Medical University,Fuzhou 350004,China,2. Undergraduate Student of 2003 Enrollment,School of Pharmacy |
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| Abstract: | Objective Nanometer Fe 3 O 4 magnetic particles were prepared via reverse microemulsion. Methods The reverse microemulsion,confected with cyclohexane,Triton X-100,n-butyl alcohol and water system,was identified by pseudoternary phase diagram. Then the microemulsion was further analyzed through conductivity measurement and colorant diffusion. Fe 3 O 4 nanoparticles were prepared by using W/O microemulsion as microreactor. The effects of molar ratios of ferric ion,ferrous ion and sodium hydroxide solution wer... |
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| Keywords: | delayed-action preparations emulsions magnetics nanotechnology drug carriers Fe 3 O 4 |
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