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上海市中小学生麻疹疫苗强化免疫的效果评价
引用本文:伍稚梅,徐天强,张金芳,赵丽丽,李秀珠.上海市中小学生麻疹疫苗强化免疫的效果评价[J].中国计划免疫,2000,6(1):11.
作者姓名:伍稚梅  徐天强  张金芳  赵丽丽  李秀珠
作者单位::伍稚梅(上海市疾病预防控制中心,上海 200031);徐天强(上海市疾病预防控制中心,上海 200031);张金芳(上海市疾病预防控制中心,上海 200031);赵丽丽(上海市疾病预防控制中心,上海 200031)
摘    要:为进一步降低上海市麻疹疫情,1994~1996年完成了中小学学生(5~19岁)一次麻疹疫苗强化免疫,共计接种1 621 454人,接种率98.19%。流行病学效果评价强化免疫前后3年平均发病率比较,5~19岁发病率由0.97/10万下降至0.15/10万,全市发病率由0.42/10万下降至0.16/10万;麻疹血凝抑制(HI)抗体,强化免疫前阴性率8%,几何平均滴度(GMT)15.53,强化免疫后阳性率100%,GMT 152.56,抗体≥4倍增长率94.4%,效果均极显著。

关 键 词:麻疹疫苗  强化免疫  效果评价
文章编号:1006-916X(2000)01-0011-03
修稿时间:1999-02-02

The Evaluation of the Effect of a Mass Campaign Immunity with Measles Vaccine to Students in Primary and Middle Schools in Shanghai
WU Zhi-mei, XU Tian-qiang, ZHANG Jin-fang,et al..The Evaluation of the Effect of a Mass Campaign Immunity with Measles Vaccine to Students in Primary and Middle Schools in Shanghai[J].Chinese Journal of Vaccines and Immunization,2000,6(1):11.
Authors:WU Zhi-mei  XU Tian-qiang  ZHANG Jin-fang  
Institution:WU Zhi-mei, XU Tian-qiang, ZHANG Jin-fang, et al.
Abstract:In order to reduce the incidence of measles in Shanghai, there carried out a mass campaign immunity with measles vaccine to students aged 5-19 years in primary and middle schools. The total of vaccination was 1621454, the rate was 98.19%. The measles average morbidity before vaccination was 0.42/100,000 and that of postvaccination was 0.16/100, 000. Before vaccination, the negative rate of measles HI antibody was 8% and the GMT of HI antibody was 1:5.53. but the HI positive rate increased to 100% and the GMT of HI antibody to 52.56% after vaccination. Fourfold increasing rate of HI antibody was 94.4%. All the data showed a very significant effect.
Keywords:Measles vaccine  Campaign immunity  Effect evaluation
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